Activates both GLP-1 and GIP receptors. Lower doses can reduce side effects while preserving some of the key metabolic benefits.
From $180.27/mo$265.00/mo
Billed quarterly with a three-month commitment paid up front.
“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”
Why GLP-1s
Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
GLP-1 receptor agonists are lab-engineered versions of this hormone, modified to resist DPP-4 breakdown and stay active long enough to sustain appetite control and blood sugar regulation.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
The result: half-lives ranging from 2.5 hours to approximately 7 days — up to 5,000 times longer than the natural hormone.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
GLP-1 RA MECHANISM OF ACTION
Step 1
Your gut releases two metabolic hormones after eating: GLP-1 and GIP. Both regulate blood sugar, appetite, and energy use, but they break down in minutes. Tirzepatide activates both pathways and lasts roughly 5 days.
Step 2
Tirzepatide side effects may scale with dose. In clinical trials, cutting the dose from 15 mg to 5 mg reduced nausea by one-third.
Step 3
Research suggests that low dose tirzepatide can activate longevity-relevant pathways including moderate weight loss, glycemic control, and anti-inflammatory effects.
ABOUT MICRODOSE TIRZEPATIDE
Personalized microdosing for longevity protocols
From $166.67/mo$245.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for type 2 diabetes
From $25.00/mo$40.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for menopausal symptoms
From $26.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for type 2 diabetes
From $20.00/mo$35.00/mo
Billed quarterly with a three-month commitment paid up front.
May support hair growth
From $13.33/mo$30.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for ED
From $24.00/mo$40.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved to treat photoaging
From $25.00/mo$45.00/mo
Billed quarterly with a three-month commitment paid up front.
Personalized peptide for growth hormone support
From $118.93/mo$165.00/mo
Billed quarterly with a three-month commitment paid up front.
Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.
Get a RecommendationCompounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.
Activates both GLP-1 and GIP receptors. Lower doses can reduce side effects while preserving some of the key metabolic benefits.
From $180.27/mo$265.00/mo
Billed quarterly with a three-month commitment paid up front.
“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”
Why GLP-1s
Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
GLP-1 receptor agonists are lab-engineered versions of this hormone, modified to resist DPP-4 breakdown and stay active long enough to sustain appetite control and blood sugar regulation.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
The result: half-lives ranging from 2.5 hours to approximately 7 days — up to 5,000 times longer than the natural hormone.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
GLP-1 RA MECHANISM OF ACTION
Step 1
Your gut releases two metabolic hormones after eating: GLP-1 and GIP. Both regulate blood sugar, appetite, and energy use, but they break down in minutes. Tirzepatide activates both pathways and lasts roughly 5 days.
Step 2
Tirzepatide side effects may scale with dose. In clinical trials, cutting the dose from 15 mg to 5 mg reduced nausea by one-third.
Step 3
Research suggests that low dose tirzepatide can activate longevity-relevant pathways including moderate weight loss, glycemic control, and anti-inflammatory effects.
ABOUT MICRODOSE TIRZEPATIDE
Personalized microdosing for longevity protocols
From $166.67/mo$245.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for type 2 diabetes
From $25.00/mo$40.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for menopausal symptoms
From $26.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for type 2 diabetes
From $20.00/mo$35.00/mo
Billed quarterly with a three-month commitment paid up front.
May support hair growth
From $13.33/mo$30.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved for ED
From $24.00/mo$40.00/mo
Billed quarterly with a three-month commitment paid up front.
FDA-approved to treat photoaging
From $25.00/mo$45.00/mo
Billed quarterly with a three-month commitment paid up front.
Personalized peptide for growth hormone support
From $118.93/mo$165.00/mo
Billed quarterly with a three-month commitment paid up front.
Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.
Get a RecommendationCompounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.