Personalized Tirzepatide (Injections)
Can activate both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety.
Support women's healthSupport longevity
EstradiolGeneric for Estrace®
Can support vaginal tissue as estrogen declines with age.
HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians
“Topical estradiol supports healthy vaginal tissue and reduces UTI recurrence, supporting longevity long past menopause.”
Why Estradiol
Estrogen production declines over time. Estradiol can help restore it.
Supports vaginal tissue
After menopause, vaginal tissue thins and becomes fragile. In a trial of 550 postmenopausal women, low-dose estradiol cream significantly restored tissue health compared to a placebo cream.
Source: Kroll et al., "A Randomized, Multicenter, Double-Blind Study to Evaluate the Safety and Efficacy of Estradiol Vaginal Cream 0.003%," Menopause (2018)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.
HOW ESTRADIOL WORKS
Replenish estrogen. Restore vitality.
Estradiol works locally on vaginal tissue. This can support tissue health, sexual function, and urinary health.
Estrogen delivered locally
Estradiol cream is applied directly to vaginal tissue. It absorbs locally, with decreased risk of elevating estrogen levels elsewhere in the body.
Tissue revitalized
Vaginal, urethral, and bladder tissue absorbs estradiol locally. This can help restore epithelial thickness, moisture, and acidic pH.
Healthy pH restored
As acidic pH returns, Lactobacillus can thrive again. This protective bacteria may help ease dryness, painful sex, recurrent UTIs, and incontinence.
How Immortals Medicine works
From intake to your door in three to seven days
Step 1Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4Unlimited messaging
Your doctor is available by message any time for additional support. Video consults available.
Up to 12 months
Get Started
The same prescription framework as Bryan Johnson's medical team.
*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Keep exploring longevity.
Personalized Semaglutide (Injections)
Can help suppress appetite and slow digestion.
Zepbound® (Kwikpen®)
Activates both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety.
Wegovy® (Injections)
Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.
Wegovy® (Tablets)
Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.
Foundayo® (Tablets)
Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.
Tirzepatide Microdose (Injections)
Activates both GLP-1 and GIP receptors.
Semaglutide Microdose (Injections)
Activates the GLP-1 pathway at lower doses.
Why Immortals Medicine
Precision medicine protocols to support longevity
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.
COMMON QUESTIONS
Questions, answered
This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program