Immortals Medicine
Sign InSign UpGet a Recommendation
  1. Home
  2. Have better sex
  3. Daily Tadalafil (Generic for Cialis®)
Daily Tadalafil

“Tadalafil enhances my endothelial function, reduces my inflammation markers, and potentially protects me against age-related cardiovascular and metabolic decline.”

Bryan Johnson
– Bryan Johnson
What Bryan takesSupport longevityHave better sex

Daily TadalafilGeneric for Cialis®

From $24/mo$40/mo

Can help relax blood vessels, supporting sexual function, vascular health, and healthy aging.

Medication Type

Daily TadalafilDaily Cialis®
HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians

$0

Membership fees

Get Started

Not sure? Take the quiz

“Tadalafil enhances my endothelial function, reduces my inflammation markers, and potentially protects me against age-related cardiovascular and metabolic decline.”

Bryan Johnson
– Bryan Johnson

Why Tadalafil

Blood vessels tighten as you age. Tadalafil helps keep them open.

With tadalafil
Without tadalafil

May lower early death risk

A study of over 29,000 men found tadalafil users had a 44% lower risk of dying from any cause compared to non-users. Groups were matched for blood pressure, diabetes, and cholesterol medications.

Source: Kloner et al., "The Association of Tadalafil Exposure With Lower Rates of Major Adverse Cardiovascular Events and Mortality," Clinical Cardiology (2024)


Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

Get Started

HOW TADALAFIL WORKS

Opens blood vessels. Supports circulation.

Tadalafil works on one enzyme in your vascular system. This single action supports vascular health, sexual function, and longevity.

connector
connector
connector

PDE5 inhibited

Tadalafil inhibits PDE5, the enzyme that breaks down cGMP, the chemical signal that keeps blood vessels relaxed.

cGMP preserved

cGMP can then stay active longer. This helps blood vessels stay relaxed which can help keep circulation running smoothly.

Daily Tadalafil (Generic for Cialis®)

Vascular function supported

This vasodilation effect has been shown to help support sexual function (the FDA-approved use). But the same effect works throughout your vascular system. Daily low-dose use may also support cardiovascular and endothelial health.

Daily Tadalafil (Generic for Cialis®)

PDE5 inhibited

Tadalafil inhibits PDE5, the enzyme that breaks down cGMP, the chemical signal that keeps blood vessels relaxed.

cGMP preserved

cGMP can then stay active longer. This helps blood vessels stay relaxed which can help keep circulation running smoothly.

Vascular function supported

This vasodilation effect has been shown to help support sexual function (the FDA-approved use). But the same effect works throughout your vascular system. Daily low-dose use may also support cardiovascular and endothelial health.

How Immortals Medicine works

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson's medical team.

  1. Person completing a medical intake on their phone
    Step 1

    Medical intake

    Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

    A few minutes
  2. A physician reviewing a patient intake
    Step 2

    Doctor review

    A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

    Within 72 hours
  3. A discreet medication package at a doorstep
    Step 3

    Fast shipping

    Approved medications ship directly to your door in discreet packaging.

    2-5 business days
  4. Person messaging their doctor from home
    Step 4

    Unlimited messaging

    Your doctor is available by message any time for additional support. Video consults available.

    Up to 12 months
Get Started

The same prescription framework as Bryan Johnson's medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

Keep exploring longevity.

Tirzepatide Microdose (Injections)

Tirzepatide Microdose (Injections)

Activates both GLP-1 and GIP receptors.

Get StartedLearn More
Semaglutide Microdose (Injections)

Semaglutide Microdose (Injections)

Activates the GLP-1 pathway at lower doses.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Stimulates the pituitary gland's natural release of growth hormone.

Get StartedLearn More
NAD+ (Injections)

NAD+ (Injections)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Injections)

Glutathione (Injections)

Can help defend cells against oxidative damage.

Get StartedLearn More
NAD+ (Nasal Spray)

NAD+ (Nasal Spray)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Nasal Spray)

Glutathione (Nasal Spray)

Can help defend cells against oxidative damage.

Get StartedLearn More
Peptide Skin Complex (4-in-1)

Peptide Skin Complex (4-in-1)

Helps reduce fine lines, fade dark spots, and brighten skin tone.

Get StartedLearn More

Why Immortals Medicine

Precision medicine protocols to support longevity

Proactive care

Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

Transparent pricing

No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

Board-certified doctors

Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

Curated by longevity experts

Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program

Explore

  • Explore Blueprint
  • Explore Biomarkers
  • Help Center
  • Careers
  • Accessibility

Follow us

Immortals Socials

InstagramTikTok

Bryan Johnson Socials

XYouTubeTikTokInstagram
Copyright © 2026 Immortals Medicine|Privacy Policy|Terms of Service

This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.

  1. Home
  2. Have better sex
  3. Daily Tadalafil (Generic for Cialis®)
Daily Tadalafil

“Tadalafil enhances my endothelial function, reduces my inflammation markers, and potentially protects me against age-related cardiovascular and metabolic decline.”

Bryan Johnson
– Bryan Johnson
What Bryan takesSupport longevityHave better sex

Daily TadalafilGeneric for Cialis®

From $24/mo$40/mo

Can help relax blood vessels, supporting sexual function, vascular health, and healthy aging.

Medication Type

Daily TadalafilDaily Cialis®
HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians

$0

Membership fees

Get Started

Not sure? Take the quiz

“Tadalafil enhances my endothelial function, reduces my inflammation markers, and potentially protects me against age-related cardiovascular and metabolic decline.”

Bryan Johnson
– Bryan Johnson

Why Tadalafil

Blood vessels tighten as you age. Tadalafil helps keep them open.

With tadalafil
Without tadalafil

May lower early death risk

A study of over 29,000 men found tadalafil users had a 44% lower risk of dying from any cause compared to non-users. Groups were matched for blood pressure, diabetes, and cholesterol medications.

Source: Kloner et al., "The Association of Tadalafil Exposure With Lower Rates of Major Adverse Cardiovascular Events and Mortality," Clinical Cardiology (2024)


Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

Get Started

HOW TADALAFIL WORKS

Opens blood vessels. Supports circulation.

Tadalafil works on one enzyme in your vascular system. This single action supports vascular health, sexual function, and longevity.

connector
connector
connector

PDE5 inhibited

Tadalafil inhibits PDE5, the enzyme that breaks down cGMP, the chemical signal that keeps blood vessels relaxed.

cGMP preserved

cGMP can then stay active longer. This helps blood vessels stay relaxed which can help keep circulation running smoothly.

Daily Tadalafil (Generic for Cialis®)

Vascular function supported

This vasodilation effect has been shown to help support sexual function (the FDA-approved use). But the same effect works throughout your vascular system. Daily low-dose use may also support cardiovascular and endothelial health.

Daily Tadalafil (Generic for Cialis®)

PDE5 inhibited

Tadalafil inhibits PDE5, the enzyme that breaks down cGMP, the chemical signal that keeps blood vessels relaxed.

cGMP preserved

cGMP can then stay active longer. This helps blood vessels stay relaxed which can help keep circulation running smoothly.

Vascular function supported

This vasodilation effect has been shown to help support sexual function (the FDA-approved use). But the same effect works throughout your vascular system. Daily low-dose use may also support cardiovascular and endothelial health.

How Immortals Medicine works

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson's medical team.

  1. Person completing a medical intake on their phone
    Step 1

    Medical intake

    Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

    A few minutes
  2. A physician reviewing a patient intake
    Step 2

    Doctor review

    A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

    Within 72 hours
  3. A discreet medication package at a doorstep
    Step 3

    Fast shipping

    Approved medications ship directly to your door in discreet packaging.

    2-5 business days
  4. Person messaging their doctor from home
    Step 4

    Unlimited messaging

    Your doctor is available by message any time for additional support. Video consults available.

    Up to 12 months
Get Started

The same prescription framework as Bryan Johnson's medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

Keep exploring longevity.

Tirzepatide Microdose (Injections)

Tirzepatide Microdose (Injections)

Activates both GLP-1 and GIP receptors.

Get StartedLearn More
Semaglutide Microdose (Injections)

Semaglutide Microdose (Injections)

Activates the GLP-1 pathway at lower doses.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Stimulates the pituitary gland's natural release of growth hormone.

Get StartedLearn More
NAD+ (Injections)

NAD+ (Injections)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Injections)

Glutathione (Injections)

Can help defend cells against oxidative damage.

Get StartedLearn More
NAD+ (Nasal Spray)

NAD+ (Nasal Spray)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Nasal Spray)

Glutathione (Nasal Spray)

Can help defend cells against oxidative damage.

Get StartedLearn More
Peptide Skin Complex (4-in-1)

Peptide Skin Complex (4-in-1)

Helps reduce fine lines, fade dark spots, and brighten skin tone.

Get StartedLearn More

Why Immortals Medicine

Precision medicine protocols to support longevity

Proactive care

Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

Transparent pricing

No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

Board-certified doctors

Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

Curated by longevity experts

Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program