Immortals Medicine
Sign InSign UpGet a Recommendation
  1. Home
  2. Lose weight
  3. Personalized Semaglutide (Injections)
Personalized Semaglutide

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Bryan Johnson
– Bryan Johnson
Lose weightExplore peptidesSupport longevity

Personalized SemaglutideCompounded Semaglutide with Glycine and B12

From $195.67/mo$275/mo

Can help suppress appetite and slow digestion. Personalized ingredients like Glycine and B12 may support muscle maintenance and nutrient deficiencies during a caloric deficit.

HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians

$0

Membership fees

Get Started

Not sure? Take the quiz

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Bryan Johnson
– Bryan Johnson

Why GLP-1s

Natural hormone breaks down in minutes. GLP-1s last days.

GLP-1s
Natural GLP-1

Natural GLP-1 lasts ~2 minutes

Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.

Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)


Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

The referenced clinical data are provided solely for educational and informational purposes to describe the known pharmacologic properties of the individual active ingredients. This information should not be interpreted as a claim that the compounded formulation will produce identical clinical outcomes, nor does it constitute a guarantee of therapeutic equivalence to any FDA-approved product.

Get Started

HOW GLP-1 RA WORKS

Supports feeling fuller for longer

Semaglutide is a GLP-1 receptor agonist (GLP-1 RA) that mimics the GLP-1 hormone produced in the gut. Receptors are located in the brain, gut, heart, and pancreas, where activation supports appetite regulation, blood sugar balance, and metabolic function.

connector
connector
connector

Activates GLP-1 receptors

GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.

Signals satiety

GLP-1 receptors in the brain suppress hunger and amplify fullness signals. The GLP-1 hormone can also slow digestion, extending a feeling of fullness after meals.

Personalized Semaglutide (Injections)

Supports metabolic health

GLP-1 receptor agonists have been shown in studies to lower blood pressure, improve blood sugar regulation, and reduce lipid levels and inflammatory markers. These effects appear independent of weight loss, driven by direct GLP-1 receptor activation in the heart, blood vessels, and kidneys.

Personalized Semaglutide (Injections)

Activates GLP-1 receptors

GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.

Signals satiety

GLP-1 receptors in the brain suppress hunger and amplify fullness signals. The GLP-1 hormone can also slow digestion, extending a feeling of fullness after meals.

Supports metabolic health

GLP-1 receptor agonists have been shown in studies to lower blood pressure, improve blood sugar regulation, and reduce lipid levels and inflammatory markers. These effects appear independent of weight loss, driven by direct GLP-1 receptor activation in the heart, blood vessels, and kidneys.

How Immortals Medicine works

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson's medical team.

  1. Person completing a medical intake on their phone
    Step 1

    Medical intake

    Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

    A few minutes
  2. A physician reviewing a patient intake
    Step 2

    Doctor review

    A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

    Within 72 hours
  3. A discreet medication package at a doorstep
    Step 3

    Fast shipping

    Approved medications ship directly to your door in discreet packaging.

    2-5 business days
  4. Person messaging their doctor from home
    Step 4

    Unlimited messaging

    Your doctor is available by message any time for additional support. Video consults available.

    Up to 12 months
Get Started

The same prescription framework as Bryan Johnson's medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

Keep exploring longevity.

Personalized Tirzepatide (Injections)

Personalized Tirzepatide (Injections)

Can activate both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety.

Get StartedLearn More
Zepbound® (Kwikpen®)

Zepbound® (Kwikpen®)

Activates both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety.

Get StartedLearn More
Wegovy® (Injections)

Wegovy® (Injections)

Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.

Get StartedLearn More
Wegovy® (Tablets)

Wegovy® (Tablets)

Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.

Get StartedLearn More
Foundayo® (Tablets)

Foundayo® (Tablets)

Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.

Get StartedLearn More
Tirzepatide Microdose (Injections)

Tirzepatide Microdose (Injections)

Activates both GLP-1 and GIP receptors.

Get StartedLearn More
Semaglutide Microdose (Injections)

Semaglutide Microdose (Injections)

Activates the GLP-1 pathway at lower doses.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Stimulates the pituitary gland's natural release of growth hormone.

Get StartedLearn More

Why Immortals Medicine

Precision medicine protocols to support longevity

Proactive care

Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

Transparent pricing

No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

Board-certified doctors

Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

Curated by longevity experts

Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.

Explore

  • Explore Blueprint
  • Explore Biomarkers
  • Help Center
  • Careers
  • Accessibility

Follow us

Immortals Socials

InstagramTikTok

Bryan Johnson Socials

XYouTubeTikTokInstagram
Copyright © 2026 Immortals Medicine|Privacy Policy|Terms of Service

This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.

  1. Home
  2. Lose weight
  3. Personalized Semaglutide (Injections)
Personalized Semaglutide

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Bryan Johnson
– Bryan Johnson
Lose weightExplore peptidesSupport longevity

Personalized SemaglutideCompounded Semaglutide with Glycine and B12

From $195.67/mo$275/mo

Can help suppress appetite and slow digestion. Personalized ingredients like Glycine and B12 may support muscle maintenance and nutrient deficiencies during a caloric deficit.

HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians

$0

Membership fees

Get Started

Not sure? Take the quiz

“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”

Bryan Johnson
– Bryan Johnson

Why GLP-1s

Natural hormone breaks down in minutes. GLP-1s last days.

GLP-1s
Natural GLP-1

Natural GLP-1 lasts ~2 minutes

Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.

Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)


Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

The referenced clinical data are provided solely for educational and informational purposes to describe the known pharmacologic properties of the individual active ingredients. This information should not be interpreted as a claim that the compounded formulation will produce identical clinical outcomes, nor does it constitute a guarantee of therapeutic equivalence to any FDA-approved product.

Get Started

HOW GLP-1 RA WORKS

Supports feeling fuller for longer

Semaglutide is a GLP-1 receptor agonist (GLP-1 RA) that mimics the GLP-1 hormone produced in the gut. Receptors are located in the brain, gut, heart, and pancreas, where activation supports appetite regulation, blood sugar balance, and metabolic function.

connector
connector
connector

Activates GLP-1 receptors

GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.

Signals satiety

GLP-1 receptors in the brain suppress hunger and amplify fullness signals. The GLP-1 hormone can also slow digestion, extending a feeling of fullness after meals.

Personalized Semaglutide (Injections)

Supports metabolic health

GLP-1 receptor agonists have been shown in studies to lower blood pressure, improve blood sugar regulation, and reduce lipid levels and inflammatory markers. These effects appear independent of weight loss, driven by direct GLP-1 receptor activation in the heart, blood vessels, and kidneys.

Personalized Semaglutide (Injections)

Activates GLP-1 receptors

GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.

Signals satiety

GLP-1 receptors in the brain suppress hunger and amplify fullness signals. The GLP-1 hormone can also slow digestion, extending a feeling of fullness after meals.

Supports metabolic health

GLP-1 receptor agonists have been shown in studies to lower blood pressure, improve blood sugar regulation, and reduce lipid levels and inflammatory markers. These effects appear independent of weight loss, driven by direct GLP-1 receptor activation in the heart, blood vessels, and kidneys.

How Immortals Medicine works

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson's medical team.

  1. Person completing a medical intake on their phone
    Step 1

    Medical intake

    Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

    A few minutes
  2. A physician reviewing a patient intake
    Step 2

    Doctor review

    A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

    Within 72 hours
  3. A discreet medication package at a doorstep
    Step 3

    Fast shipping

    Approved medications ship directly to your door in discreet packaging.

    2-5 business days
  4. Person messaging their doctor from home
    Step 4

    Unlimited messaging

    Your doctor is available by message any time for additional support. Video consults available.

    Up to 12 months
Get Started

The same prescription framework as Bryan Johnson's medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

Keep exploring longevity.

Personalized Tirzepatide (Injections)

Personalized Tirzepatide (Injections)

Can activate both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety.

Get StartedLearn More
Zepbound® (Kwikpen®)

Zepbound® (Kwikpen®)

Activates both GLP-1 and GIP receptors, the two gut hormones that signal appetite and satiety.

Get StartedLearn More
Wegovy® (Injections)

Wegovy® (Injections)

Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.

Get StartedLearn More
Wegovy® (Tablets)

Wegovy® (Tablets)

Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.

Get StartedLearn More
Foundayo® (Tablets)

Foundayo® (Tablets)

Activates GLP-1 receptors, the gut hormone that signals appetite and satiety.

Get StartedLearn More
Tirzepatide Microdose (Injections)

Tirzepatide Microdose (Injections)

Activates both GLP-1 and GIP receptors.

Get StartedLearn More
Semaglutide Microdose (Injections)

Semaglutide Microdose (Injections)

Activates the GLP-1 pathway at lower doses.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Stimulates the pituitary gland's natural release of growth hormone.

Get StartedLearn More

Why Immortals Medicine

Precision medicine protocols to support longevity

Proactive care

Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

Transparent pricing

No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

Board-certified doctors

Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

Curated by longevity experts

Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.