Tirzepatide Microdose (Injections)
Activates both GLP-1 and GIP receptors.
Support longevity
Semaglutide Microdose (Injections)Compounded Semaglutide with Glycine and B12
From $166.67/mo$245/mo
Microdosing semaglutide activates the GLP-1 pathway at lower doses, reducing side effects and may support longevity protocols.
HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians
$0
Membership fees
“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”
Why GLP-1s
Natural hormone breaks down in minutes. GLP-1s last days.
GLP-1s
Natural GLP-1
Natural GLP-1 lasts ~2 minutes
Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.
The referenced clinical data are provided solely for educational and informational purposes to describe the known pharmacologic properties of the individual active ingredients. This information should not be interpreted as a claim that the compounded formulation will produce identical clinical outcomes, nor does it constitute a guarantee of therapeutic equivalence to any FDA-approved product.
HOW GLP-1 RA WORKS
Semaglutide activates GLP-1 receptors throughout the body.
Semaglutide is a GLP-1 receptor agonist (GLP-1 RA) that mimics the GLP-1 hormone produced in the gut. Receptors are located in the brain, gut, heart, and pancreas, where activation supports appetite regulation, blood sugar balance, and metabolic function.
Activates GLP-1 receptors
GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.
Reduces side effects
Side effects from semaglutide are dose-dependent. In clinical trials, dropping from 2.4 mg to 1.0 mg reduced the rate of digestive side effects by 6% (absolute reduction).
Preserves benefits
Research suggests that low dose semaglutide can activate longevity-relevant pathways including moderate weight loss, glycemic control, and liver health.
How Immortals Medicine works
From intake to your door in three to seven days
Step 1Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4Unlimited messaging
Your doctor is available by message any time for additional support. Video consults available.
Up to 12 months
Get Started
The same prescription framework as Bryan Johnson's medical team.
*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Keep exploring longevity.
Sermorelin (Injections)
Stimulates the pituitary gland's natural release of growth hormone.
NAD+ (Injections)
Can replenish NAD+ levels, which naturally decline with age.
Glutathione (Injections)
Can help defend cells against oxidative damage.
NAD+ (Nasal Spray)
Can replenish NAD+ levels, which naturally decline with age.
Glutathione (Nasal Spray)
Can help defend cells against oxidative damage.
Peptide Skin Complex (4-in-1)
Helps reduce fine lines, fade dark spots, and brighten skin tone.
Metformin
Activates AMPK, the body's cellular energy switch.
Why Immortals Medicine
Precision medicine protocols to support longevity
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.
COMMON QUESTIONS
Questions, answered
Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.