Semaglutide Microdose (Injections)
Activates the GLP-1 pathway at lower doses.
Support longevity
Tirzepatide Microdose (Injections)Compounded Tirzepatide with Glycine and B12
From $180.27/mo$265/mo
Activates both GLP-1 and GIP receptors. Lower doses can reduce side effects while preserving some of the key metabolic benefits.
HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians
$0
Membership fees
“There has been growing scientific data suggesting that GLP-1 agonists are beneficial for longevity via several mechanisms that are independent from weight loss.”
Why GLP-1s
Natural hormone breaks down in minutes. GLP-1s last days.
GLP-1s
Natural GLP-1
Natural GLP-1 lasts ~2 minutes
Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.
The referenced clinical data are provided solely for educational and informational purposes to describe the known pharmacologic properties of the individual active ingredients. This information should not be interpreted as a claim that the compounded formulation will produce identical clinical outcomes, nor does it constitute a guarantee of therapeutic equivalence to any FDA-approved product.
HOW GLP-1 RA WORKS
Tirzepatide activates both GLP-1 and GIP receptors.
Tirzepatide is a GLP-1 receptor agonist that mimics the GLP-1 hormone produced in the gut. Receptors are located in the brain, gut, heart, and pancreas, where activation supports appetite regulation, blood sugar balance, and metabolic function.
Activates GLP-1 receptors
Your gut releases two metabolic hormones after eating: GLP-1 and GIP. Both regulate blood sugar, appetite, and energy use, but they break down in minutes. Tirzepatide activates both pathways and lasts roughly 5 days.
Can Reduce side effects
Tirzepatide side effects may scale with dose. In clinical trials, cutting the dose from 15 mg to 5 mg reduced nausea by one-third.
Preserves benefits
Research suggests that low dose tirzepatide can activate longevity-relevant pathways including moderate weight loss, glycemic control, and anti-inflammatory effects.
How Immortals Medicine works
From intake to your door in three to seven days
Step 1Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4Unlimited messaging
Your doctor is available by message any time for additional support. Video consults available.
Up to 12 months
Get Started
The same prescription framework as Bryan Johnson's medical team.
*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Keep exploring longevity.
Sermorelin (Injections)
Stimulates the pituitary gland's natural release of growth hormone.
NAD+ (Injections)
Can replenish NAD+ levels, which naturally decline with age.
Glutathione (Injections)
Can help defend cells against oxidative damage.
NAD+ (Nasal Spray)
Can replenish NAD+ levels, which naturally decline with age.
Glutathione (Nasal Spray)
Can help defend cells against oxidative damage.
Peptide Skin Complex (4-in-1)
Helps reduce fine lines, fade dark spots, and brighten skin tone.
Metformin
Activates AMPK, the body's cellular energy switch.
Why Immortals Medicine
Precision medicine protocols to support longevity
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.
COMMON QUESTIONS
Questions, answered
Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.