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Arousal Peptide (bremelanotide)
Women's healthBetter sexExplore peptides

Arousal Peptide (bremelanotide)

Can increase sexual desire by activating brain pathways involved in desire and arousal.

Medication type

Nasal SprayInjection

From $73.33/mo$91.67/mo

Billed quarterly with a three-month commitment paid up front.

Get Started

Not sure? Take the quiz

“In clinical trials, bremelanotide delivered 2.5–3x greater improvement in sexual desire scores across 1,200+ women.”

Carl Seger, M.D.
– Dr. Carl Seger M.D.

Why Bremelanotide

Desire starts in the brain. Bremelanotide activates the pathway.

Get Started
With bremelanotide
Without bremelanotide

In two trials of over 1,200 premenopausal women with low sexual desire, bremelanotide increased desire scores by 0.5 points versus 0.2 with placebo (p < 0.001), with benefits appearing within the first few weeks and maintained over 6 months.

Source: Kingsberg et al., "Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials," Obstetrics & Gynecology (2019) — the RECONNECT Trials

Bremelanotide also reduced emotional distress about low desire by 0.33 points more than placebo (p < 0.001), with women reporting increased feelings of desire, physical arousal, and improvements in relationship quality.

Source: Kingsberg et al., "Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials," Obstetrics & Gynecology (2019) — the RECONNECT Trials

80% of eligible women opted to continue treatment and maintained improvements in desire and distress through 18 months.

Source: Simon et al., "Long-Term Safety and Efficacy of Bremelanotide for HSDD," Obstetrics & Gynecology (2019) & Davis, "Sexual Dysfunction in Women," NEJM (2024)

BREMELANOTIDE MECHANISM OF ACTION

Activates brain pathways linked to desire.

Bremelanotide activates melanocortin receptors in the brain. These receptors are part of the neural pathway that regulates sexual desire. Unlike treatments that act on blood flow or hormones, bremelanotide works upstream at the source of desire itself.

Step 1

Activates melanocortin receptors

Bremelanotide activates melanocortin receptors in the brain, particularly the MC4R subtype, which is found in areas of the brain believed to be involved in sexual function.

Step 2

Engages dopamine pathways

This receptor activation is thought to stimulate the release of dopamine — a brain chemical associated with arousal and motivation

Step 3

Increases feelings of sexual desire

In clinical trials, women using bremelanotide reported increased feelings of sexual desire and reduced distress related to low desire.

Get Started

ABOUT AROUSAL PEPTIDE

What to know

Arousal Peptide (Injections)

Keep exploring longevity.

Arousal Peptide (Nasal Spray)

Arousal Peptide (Nasal Spray)

Formulated with bremelanotide to support libido

From $151.20/mo$210.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Men's Sex Complex (3-in-1)

Men's Sex Complex (3-in-1)

Better sex support with apomorphine, tadalafil, and vardenafil

From $47.73/mo$70.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
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FDA-approved for type 2 diabetes

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Billed quarterly with a three-month commitment paid up front.

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FDA-approved for menopausal symptoms

From $26.00/mo

Billed quarterly with a three-month commitment paid up front.

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From $20.00/mo$35.00/mo

Billed quarterly with a three-month commitment paid up front.

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Daily Tadalafil (Generic for Cialis®)

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Billed quarterly with a three-month commitment paid up front.

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FDA-approved to treat photoaging

From $25.00/mo$45.00/mo

Billed quarterly with a three-month commitment paid up front.

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Not sure where to start?

Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.

Get a Recommendation

Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.

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Arousal Peptide (bremelanotide)
Women's healthBetter sexExplore peptides

Arousal Peptide (bremelanotide)

Can increase sexual desire by activating brain pathways involved in desire and arousal.

Medication type

Nasal SprayInjection

From $73.33/mo$91.67/mo

Billed quarterly with a three-month commitment paid up front.

Get Started

Not sure? Take the quiz

“In clinical trials, bremelanotide delivered 2.5–3x greater improvement in sexual desire scores across 1,200+ women.”

Carl Seger, M.D.
– Dr. Carl Seger M.D.

Why Bremelanotide

Desire starts in the brain. Bremelanotide activates the pathway.

Get Started
With bremelanotide
Without bremelanotide

In two trials of over 1,200 premenopausal women with low sexual desire, bremelanotide increased desire scores by 0.5 points versus 0.2 with placebo (p < 0.001), with benefits appearing within the first few weeks and maintained over 6 months.

Source: Kingsberg et al., "Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials," Obstetrics & Gynecology (2019) — the RECONNECT Trials

Bremelanotide also reduced emotional distress about low desire by 0.33 points more than placebo (p < 0.001), with women reporting increased feelings of desire, physical arousal, and improvements in relationship quality.

Source: Kingsberg et al., "Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials," Obstetrics & Gynecology (2019) — the RECONNECT Trials

80% of eligible women opted to continue treatment and maintained improvements in desire and distress through 18 months.

Source: Simon et al., "Long-Term Safety and Efficacy of Bremelanotide for HSDD," Obstetrics & Gynecology (2019) & Davis, "Sexual Dysfunction in Women," NEJM (2024)

BREMELANOTIDE MECHANISM OF ACTION

Activates brain pathways linked to desire.

Bremelanotide activates melanocortin receptors in the brain. These receptors are part of the neural pathway that regulates sexual desire. Unlike treatments that act on blood flow or hormones, bremelanotide works upstream at the source of desire itself.

Step 1

Activates melanocortin receptors

Bremelanotide activates melanocortin receptors in the brain, particularly the MC4R subtype, which is found in areas of the brain believed to be involved in sexual function.

Step 2

Engages dopamine pathways

This receptor activation is thought to stimulate the release of dopamine — a brain chemical associated with arousal and motivation

Step 3

Increases feelings of sexual desire

In clinical trials, women using bremelanotide reported increased feelings of sexual desire and reduced distress related to low desire.

Get Started

ABOUT AROUSAL PEPTIDE

What to know

Arousal Peptide (Injections)

Keep exploring longevity.

Arousal Peptide (Nasal Spray)

Arousal Peptide (Nasal Spray)

Formulated with bremelanotide to support libido

From $151.20/mo$210.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Men's Sex Complex (3-in-1)

Men's Sex Complex (3-in-1)

Better sex support with apomorphine, tadalafil, and vardenafil

From $47.73/mo$70.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Acarbose

Acarbose

FDA-approved for type 2 diabetes

From $25.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Estradiol (Generic for Estrace®)

Estradiol (Generic for Estrace®)

FDA-approved for menopausal symptoms

From $26.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Metformin

Metformin

FDA-approved for type 2 diabetes

From $20.00/mo$35.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Oral Minoxidil

Oral Minoxidil

May support hair growth

From $13.33/mo$30.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Daily Tadalafil (Generic for Cialis®)

Daily Tadalafil (Generic for Cialis®)

FDA-approved for ED

From $24.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Tretinoin

Tretinoin

FDA-approved to treat photoaging

From $25.00/mo$45.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More

Not sure where to start?

Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.

Get a Recommendation

Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.