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Women’s Skin Complex (4-in-1)
Renew skinWomen's health

Women’s Skin Complex (4-in-1)

A 4-in-1 topical cream combining estriol, finasteride, tretinoin, and niacinamide to target visible signs of aging.

From $64.53/mo$95.00/mo

Billed quarterly with a three-month commitment paid up front.

Get Started

Not sure? Take the quiz

“I reversed my skin age by the equivalent of 9 years. Effectively freezing my skin aging over the past five years. Tretinoin is a core part of my skincare protocol.”

Bryan Johnson
– Bryan Johnson

Why Tretinoin

Increases skin cell turnover. Improves photoaged skin.

Get Started
With tretinoin
Without tretinoin

In a 6-month trial of nearly 300 adults with sun-damaged skin, 68% using tretinoin showed overall skin improvement.

Source: Olsen et al., "Tretinoin Emollient Cream: A New Therapy for Photodamaged Skin," Journal of the American Academy of Dermatology (1992) & Stern, "Treatment of Photoaging," New England Journal of Medicine (2004)

The trial found tretinoin was effective at reducing fine wrinkles, uneven brown spots (mottled hyperpigmentation), and rough skin texture.

Source: Olsen et al., "Tretinoin Emollient Cream: A New Therapy for Photodamaged Skin," Journal of the American Academy of Dermatology (1992) & Stern, "Treatment of Photoaging," New England Journal of Medicine (2004)

Across multiple similar trials, the rate of improvement with tretinoin was roughly double that of placebo.

Source: Olsen et al., "Tretinoin Emollient Cream: A New Therapy for Photodamaged Skin," Journal of the American Academy of Dermatology (1992) & Stern, "Treatment of Photoaging," New England Journal of Medicine (2004)

WOMEN’S SKIN COMPLEX MECHANISM OF ACTION

Rebuilds collagen. Improves skin texture.

Tretinoin switches on genes responsible for producing collagen and regulating pigmentation. Niacinamide evens tone at the surface. Estriol hydrates the skin and increases elasticity. Finasteride blocks DHT, minimizing unwanted facial hair.

Step 1

Accelerates cell turnover

Dead skin cells shed faster. New cells reach the surface more quickly, improving texture and tone.

Step 2

Stimulates collagen production

Fibroblasts are activated to produce new collagen, partially reversing structural damage from UV exposure.

Step 3

Strengthens and restores skin

Estriol supports hydration and elasticity, while niacinamide strengthens the skin barrier, reduces redness, and brightens tone.

Get Started

ABOUT WOMEN’S Skin Complex

What to know

Women's Skin Complex (4-in-1)

Keep exploring longevity.

Tretinoin

Tretinoin

FDA-approved to treat photoaging

From $25.00/mo$45.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Peptide Skin Complex (4-in-1)

Peptide Skin Complex (4-in-1)

Anti-aging topical with tretinoin, GHK-Cu, caffeine and niacinamide

From $133.33/mo$185.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Acarbose

Acarbose

FDA-approved for type 2 diabetes

From $25.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Estradiol (Generic for Estrace®)

Estradiol (Generic for Estrace®)

FDA-approved for menopausal symptoms

From $26.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Metformin

Metformin

FDA-approved for type 2 diabetes

From $20.00/mo$35.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Oral Minoxidil

Oral Minoxidil

May support hair growth

From $13.33/mo$30.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Daily Tadalafil (Generic for Cialis®)

Daily Tadalafil (Generic for Cialis®)

FDA-approved for ED

From $24.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Personalized peptide for growth hormone support

From $118.93/mo$165.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More

Not sure where to start?

Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.

Get a Recommendation

Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.

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Women’s Skin Complex (4-in-1)
Renew skinWomen's health

Women’s Skin Complex (4-in-1)

A 4-in-1 topical cream combining estriol, finasteride, tretinoin, and niacinamide to target visible signs of aging.

From $64.53/mo$95.00/mo

Billed quarterly with a three-month commitment paid up front.

Get Started

Not sure? Take the quiz

“I reversed my skin age by the equivalent of 9 years. Effectively freezing my skin aging over the past five years. Tretinoin is a core part of my skincare protocol.”

Bryan Johnson
– Bryan Johnson

Why Tretinoin

Increases skin cell turnover. Improves photoaged skin.

Get Started
With tretinoin
Without tretinoin

In a 6-month trial of nearly 300 adults with sun-damaged skin, 68% using tretinoin showed overall skin improvement.

Source: Olsen et al., "Tretinoin Emollient Cream: A New Therapy for Photodamaged Skin," Journal of the American Academy of Dermatology (1992) & Stern, "Treatment of Photoaging," New England Journal of Medicine (2004)

The trial found tretinoin was effective at reducing fine wrinkles, uneven brown spots (mottled hyperpigmentation), and rough skin texture.

Source: Olsen et al., "Tretinoin Emollient Cream: A New Therapy for Photodamaged Skin," Journal of the American Academy of Dermatology (1992) & Stern, "Treatment of Photoaging," New England Journal of Medicine (2004)

Across multiple similar trials, the rate of improvement with tretinoin was roughly double that of placebo.

Source: Olsen et al., "Tretinoin Emollient Cream: A New Therapy for Photodamaged Skin," Journal of the American Academy of Dermatology (1992) & Stern, "Treatment of Photoaging," New England Journal of Medicine (2004)

WOMEN’S SKIN COMPLEX MECHANISM OF ACTION

Rebuilds collagen. Improves skin texture.

Tretinoin switches on genes responsible for producing collagen and regulating pigmentation. Niacinamide evens tone at the surface. Estriol hydrates the skin and increases elasticity. Finasteride blocks DHT, minimizing unwanted facial hair.

Step 1

Accelerates cell turnover

Dead skin cells shed faster. New cells reach the surface more quickly, improving texture and tone.

Step 2

Stimulates collagen production

Fibroblasts are activated to produce new collagen, partially reversing structural damage from UV exposure.

Step 3

Strengthens and restores skin

Estriol supports hydration and elasticity, while niacinamide strengthens the skin barrier, reduces redness, and brightens tone.

Get Started

ABOUT WOMEN’S Skin Complex

What to know

Women's Skin Complex (4-in-1)

Keep exploring longevity.

Tretinoin

Tretinoin

FDA-approved to treat photoaging

From $25.00/mo$45.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Peptide Skin Complex (4-in-1)

Peptide Skin Complex (4-in-1)

Anti-aging topical with tretinoin, GHK-Cu, caffeine and niacinamide

From $133.33/mo$185.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Acarbose

Acarbose

FDA-approved for type 2 diabetes

From $25.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Estradiol (Generic for Estrace®)

Estradiol (Generic for Estrace®)

FDA-approved for menopausal symptoms

From $26.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Metformin

Metformin

FDA-approved for type 2 diabetes

From $20.00/mo$35.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Oral Minoxidil

Oral Minoxidil

May support hair growth

From $13.33/mo$30.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Daily Tadalafil (Generic for Cialis®)

Daily Tadalafil (Generic for Cialis®)

FDA-approved for ED

From $24.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Personalized peptide for growth hormone support

From $118.93/mo$165.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More

Not sure where to start?

Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.

Get a Recommendation

Compounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.