In the 12-week US trial, men taking as-needed tadalafil successfully completed intercourse in 67.6% of attempts, compared to only 24.1% with placebo
Source: Seftel AD, Wilson SK, Knapp PM, et al. The Journal of Urology (2004)
Better sex
Men’s Sex Complex (3-in-1)
A 3-in-1 formulation of apomorphine, tadalafil, and vardenafil to support men’s sexual performance.
From $47.73/mo$70.00/mo
Billed quarterly with a three-month commitment paid up front.
“ED is common, but most don’t talk about it. 40% haven’t even told their doctor. There’s stigma around using interventions, as the perception is it makes you less of a man. If you’re not performing how you’d like, there are many paths to improvement. There’s no shame in this and in fact will make you more of a man to address it head on.”
Why Men's Sex Complex
Sexual response depends on both the brain and blood flow. Men's Sex Complex supports multiple pathways.
With tadalafil
Without tadalafil
82.8% of tadalafil-treated men reported improved erections on the Global Assessment Question, versus 19.6% on placebo.
Source: Seftel AD, Wilson SK, Knapp PM, et al. The Journal of Urology (2004)
Across 7 pivotal trials (>4,000 patients), as-needed tadalafil improved IIEF Erectile Function domain scores by +5.6 to +8.0 points
Source: Tadalafil. FDA Drug Label. Food and Drug Administration. (2024)
MEN’S SEX COMPLEX MECHANISM OF ACTION
Heightens arousal. Improves performance.
Apomorphine activates dopamine receptors in the brain which has been studied for enhancing sexual response. Tadalafil and vardenafil both block the PDE5 enzyme, which can help improve circulation to support erectile function.
Step 1
Activates desire signals
Apomorphine stimulates dopamine receptors in the hypothalamus and limbic system, initiating the signals that drive sexual arousal independent of blood flow.
Step 2
Inhibits PDE5
Tadalafil and vardenafil block PDE5, the enzyme that breaks down nitric oxide, the chemical signal that tells blood vessels to relax.
Step 3
Preserves nitric oxide
With PDE5 inhibited, the nitric oxide signal lasts longer. Blood vessels stay relaxed and circulation stays open, supporting erectile response.
ABOUT MEN’S SEX COMPOUND (3-in-1)
What to know
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Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.
Get a RecommendationCompounded medications are not FDA-approved, and the FDA does not evaluate them for safety, effectiveness, or quality prior to use. This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment.