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  3. Jardiance®
Jardiance® (empagliflozin)

“I take Jardiance®, an SGLT-2 inhibitor, daily. There is good preclinical evidence supporting SGLT-2 inhibitors as longevity interventions and calorie restriction mimetics, complemented by robust human trial data showing heart and kidney protection.”

Bryan Johnson
– Bryan Johnson
What Bryan takesSupport longevitySupport weight loss

Jardiance®(empagliflozin)

From $1200/mo$1500/mo

Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar.

HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians

$0

Membership fees

Get Started

Not sure? Take the quiz

“I take Jardiance®, an SGLT-2 inhibitor, daily. There is good preclinical evidence supporting SGLT-2 inhibitors as longevity interventions and calorie restriction mimetics, complemented by robust human trial data showing heart and kidney protection.”

Bryan Johnson
– Bryan Johnson

Why Jardiance®

Your kidneys reabsorb glucose. Jardiance® reduces that reabsorption.

With Jardiance®
Without Jardiance®

Rapidly cuts sugar reabsorption

In a study of 30 people — half with type 2 diabetes and half without — Jardiance® reduced the kidneys' maximum sugar-recycling capacity by 44–53% within just 2 days, and by 65–75% after 14 days.

Source: Al-Jobori et al., "Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes," Diabetes (2017)


Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

Get Started

HOW JARDIANCE® WORKS

Lowers glucose. Supports metabolic health.

Jardiance® inhibits SGLT2 in the kidneys, the transporter that pulls glucose and sodium back into your blood. This helps support cardiovascular health, kidney function, and metabolic health.

connector
connector
connector

Inhibits SGLT2

Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.

Helps excrete glucose and sodium

With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.

Jardiance®

Reduces cardiometabolic load

In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.

Jardiance®

Inhibits SGLT2

Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.

Helps excrete glucose and sodium

With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.

Reduces cardiometabolic load

In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.

How Immortals Medicine works

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson's medical team.

  1. Person completing a medical intake on their phone
    Step 1

    Medical intake

    Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

    A few minutes
  2. A physician reviewing a patient intake
    Step 2

    Doctor review

    A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

    Within 72 hours
  3. A discreet medication package at a doorstep
    Step 3

    Fast shipping

    Approved medications ship directly to your door in discreet packaging.

    2-5 business days
  4. Person messaging their doctor from home
    Step 4

    Unlimited messaging

    Your doctor is available by message any time for additional support. Video consults available.

    Up to 12 months
Get Started

The same prescription framework as Bryan Johnson's medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

Keep exploring longevity.

Tirzepatide Microdose (Injections)

Tirzepatide Microdose (Injections)

Activates both GLP-1 and GIP receptors.

Get StartedLearn More
Semaglutide Microdose (Injections)

Semaglutide Microdose (Injections)

Activates the GLP-1 pathway at lower doses.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Stimulates the pituitary gland's natural release of growth hormone.

Get StartedLearn More
NAD+ (Injections)

NAD+ (Injections)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Injections)

Glutathione (Injections)

Can help defend cells against oxidative damage.

Get StartedLearn More
NAD+ (Nasal Spray)

NAD+ (Nasal Spray)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Nasal Spray)

Glutathione (Nasal Spray)

Can help defend cells against oxidative damage.

Get StartedLearn More
Peptide Skin Complex (4-in-1)

Peptide Skin Complex (4-in-1)

Helps reduce fine lines, fade dark spots, and brighten skin tone.

Get StartedLearn More

Why Immortals Medicine

Precision medicine protocols to support longevity

Proactive care

Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

Transparent pricing

No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

Board-certified doctors

Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

Curated by longevity experts

Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program

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This website is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.

  1. Home
  2. Lose weight
  3. Jardiance®
Jardiance® (empagliflozin)

“I take Jardiance®, an SGLT-2 inhibitor, daily. There is good preclinical evidence supporting SGLT-2 inhibitors as longevity interventions and calorie restriction mimetics, complemented by robust human trial data showing heart and kidney protection.”

Bryan Johnson
– Bryan Johnson
What Bryan takesSupport longevitySupport weight loss

Jardiance®(empagliflozin)

From $1200/mo$1500/mo

Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar.

HSA/FSA reimbursable
Founded by Bryan Johnson
No insurance required
Fast, discreet shipping
Licensed US pharmacies
Unlimited follow-up with licensed physicians
HSA/FSA reimbursable
No insurance required
Licensed US pharmacies
Founded by Bryan Johnson
Fast, discreet shipping
Unlimited follow-up with licensed physicians

$0

Membership fees

Get Started

Not sure? Take the quiz

“I take Jardiance®, an SGLT-2 inhibitor, daily. There is good preclinical evidence supporting SGLT-2 inhibitors as longevity interventions and calorie restriction mimetics, complemented by robust human trial data showing heart and kidney protection.”

Bryan Johnson
– Bryan Johnson

Why Jardiance®

Your kidneys reabsorb glucose. Jardiance® reduces that reabsorption.

With Jardiance®
Without Jardiance®

Rapidly cuts sugar reabsorption

In a study of 30 people — half with type 2 diabetes and half without — Jardiance® reduced the kidneys' maximum sugar-recycling capacity by 44–53% within just 2 days, and by 65–75% after 14 days.

Source: Al-Jobori et al., "Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes," Diabetes (2017)


Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.

Get Started

HOW JARDIANCE® WORKS

Lowers glucose. Supports metabolic health.

Jardiance® inhibits SGLT2 in the kidneys, the transporter that pulls glucose and sodium back into your blood. This helps support cardiovascular health, kidney function, and metabolic health.

connector
connector
connector

Inhibits SGLT2

Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.

Helps excrete glucose and sodium

With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.

Jardiance®

Reduces cardiometabolic load

In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.

Jardiance®

Inhibits SGLT2

Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.

Helps excrete glucose and sodium

With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.

Reduces cardiometabolic load

In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.

How Immortals Medicine works

From intake to your door in three to seven days

Get Started

The same prescription framework as Bryan Johnson's medical team.

  1. Person completing a medical intake on their phone
    Step 1

    Medical intake

    Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

    A few minutes
  2. A physician reviewing a patient intake
    Step 2

    Doctor review

    A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

    Within 72 hours
  3. A discreet medication package at a doorstep
    Step 3

    Fast shipping

    Approved medications ship directly to your door in discreet packaging.

    2-5 business days
  4. Person messaging their doctor from home
    Step 4

    Unlimited messaging

    Your doctor is available by message any time for additional support. Video consults available.

    Up to 12 months
Get Started

The same prescription framework as Bryan Johnson's medical team.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

Keep exploring longevity.

Tirzepatide Microdose (Injections)

Tirzepatide Microdose (Injections)

Activates both GLP-1 and GIP receptors.

Get StartedLearn More
Semaglutide Microdose (Injections)

Semaglutide Microdose (Injections)

Activates the GLP-1 pathway at lower doses.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Stimulates the pituitary gland's natural release of growth hormone.

Get StartedLearn More
NAD+ (Injections)

NAD+ (Injections)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Injections)

Glutathione (Injections)

Can help defend cells against oxidative damage.

Get StartedLearn More
NAD+ (Nasal Spray)

NAD+ (Nasal Spray)

Can replenish NAD+ levels, which naturally decline with age.

Get StartedLearn More
Glutathione (Nasal Spray)

Glutathione (Nasal Spray)

Can help defend cells against oxidative damage.

Get StartedLearn More
Peptide Skin Complex (4-in-1)

Peptide Skin Complex (4-in-1)

Helps reduce fine lines, fade dark spots, and brighten skin tone.

Get StartedLearn More

Why Immortals Medicine

Precision medicine protocols to support longevity

Proactive care

Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

Transparent pricing

No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

Board-certified doctors

Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

Curated by longevity experts

Every protocol is built by medical experts, based on longevity research from Bryan Johnson's science team.

COMMON QUESTIONS

Questions, answered

This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program