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Jardiance® (empagliflozin)
What Bryan TakesSupport longevityLose weight

Jardiance® (empagliflozin)

Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar.

From $1200.00/mo$1500.00/mo

Billed monthly.

Get Started

Not sure? Take the quiz

“I take Jardiance daily. There is good evidence of SGLT2 inhibitors as a longevity intervention and calorie restriction mimetic from animal experimentation.”

Bryan Johnson
– Bryan Johnson

Why Jardiance®

Your kidneys reabsorb glucose. Jardiance® reduces that reabsorption.

Get Started
With Jardiance®
Without Jardiance®

In a study of 30 people — half with type 2 diabetes and half without — Jardiance® reduced the kidneys' maximum sugar-recycling capacity by 44–53% within just 2 days, and by 65–75% after 14 days.

Source: Al-Jobori et al., "Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes," Diabetes (2017)

Patients taking Jardiance® excrete approximately 64 grams of sugar per day with the 10 mg dose and 78 grams per day with the 25 mg dose — that's roughly equivalent to 16–20 teaspoons of sugar being removed from the body every day.

Source: Jardiance (empagliflozin) FDA Prescribing Information (2026) & Heise et al., "Pharmacodynamic Effects of Single and Multiple Doses of Empagliflozin," Clinical Therapeutics (2016)

In the landmark EMPA-REG OUTCOME trial, empagliflozin reduced cardiovascular death by 38% and slowed kidney disease progression by 39% in patients with type 2 diabetes and heart disease.

Source: Braunwald, "Gliflozins in the Management of Cardiovascular Disease," New England Journal of Medicine (2022) & Jardiance FDA-Approved Indications (2026)

JARDIANCE® MECHANISM OF ACTION

Lowers glucose. Supports metabolic health.

Jardiance® inhibits SGLT2 in the kidneys, the transporter that pulls glucose and sodium back into your blood. This helps support cardiovascular health, kidney function, and metabolic health.

Step 1

Inhibits SGLT2

Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.

Step 2

Helps excrete glucose and sodium

With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.

Step 3

Reduces cardiometabolic load

In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.

Get Started

ABOUT JARDIANCE®

What to know

Jardiance®

Keep exploring longevity.

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Not sure where to start?

Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.

Get a Recommendation

This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program

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Jardiance® (empagliflozin)
What Bryan TakesSupport longevityLose weight

Jardiance® (empagliflozin)

Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar.

From $1200.00/mo$1500.00/mo

Billed monthly.

Get Started

Not sure? Take the quiz

“I take Jardiance daily. There is good evidence of SGLT2 inhibitors as a longevity intervention and calorie restriction mimetic from animal experimentation.”

Bryan Johnson
– Bryan Johnson

Why Jardiance®

Your kidneys reabsorb glucose. Jardiance® reduces that reabsorption.

Get Started
With Jardiance®
Without Jardiance®

In a study of 30 people — half with type 2 diabetes and half without — Jardiance® reduced the kidneys' maximum sugar-recycling capacity by 44–53% within just 2 days, and by 65–75% after 14 days.

Source: Al-Jobori et al., "Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes," Diabetes (2017)

Patients taking Jardiance® excrete approximately 64 grams of sugar per day with the 10 mg dose and 78 grams per day with the 25 mg dose — that's roughly equivalent to 16–20 teaspoons of sugar being removed from the body every day.

Source: Jardiance (empagliflozin) FDA Prescribing Information (2026) & Heise et al., "Pharmacodynamic Effects of Single and Multiple Doses of Empagliflozin," Clinical Therapeutics (2016)

In the landmark EMPA-REG OUTCOME trial, empagliflozin reduced cardiovascular death by 38% and slowed kidney disease progression by 39% in patients with type 2 diabetes and heart disease.

Source: Braunwald, "Gliflozins in the Management of Cardiovascular Disease," New England Journal of Medicine (2022) & Jardiance FDA-Approved Indications (2026)

JARDIANCE® MECHANISM OF ACTION

Lowers glucose. Supports metabolic health.

Jardiance® inhibits SGLT2 in the kidneys, the transporter that pulls glucose and sodium back into your blood. This helps support cardiovascular health, kidney function, and metabolic health.

Step 1

Inhibits SGLT2

Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.

Step 2

Helps excrete glucose and sodium

With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.

Step 3

Reduces cardiometabolic load

In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.

Get Started

ABOUT JARDIANCE®

What to know

Jardiance®

Keep exploring longevity.

Acarbose

Acarbose

FDA-approved for type 2 diabetes

From $25.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Metformin

Metformin

FDA-approved for type 2 diabetes

From $20.00/mo$35.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Brenzavvy®

Brenzavvy®

FDA-approved for type 2 diabetes

From $142.80/mo$210.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Estradiol (Generic for Estrace®)

Estradiol (Generic for Estrace®)

FDA-approved for menopausal symptoms

From $26.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Oral Minoxidil

Oral Minoxidil

May support hair growth

From $13.33/mo$30.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Daily Tadalafil (Generic for Cialis®)

Daily Tadalafil (Generic for Cialis®)

FDA-approved for ED

From $24.00/mo$40.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Tretinoin

Tretinoin

FDA-approved to treat photoaging

From $25.00/mo$45.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More
Sermorelin (Injections)

Sermorelin (Injections)

Personalized peptide for growth hormone support

From $118.93/mo$165.00/mo

Billed quarterly with a three-month commitment paid up front.

Get StartedLearn More

Not sure where to start?

Answer a few quick questions and we'll match you with the best option for your goals. A physician reviews every recommendation, and there is no charge until your prescription is approved.

Get a Recommendation

This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program