Brenzavvy blocks SGLT2, a protein that pulls sugar back into the bloodstream. Excess glucose exits through urine instead.
Source: FDA-Approved Prescribing Information for Bexagliflozin (Brenzavvy), 2025
Support longevityLose weight
Brenzavvy® (bexagliflozin)
Can help kidneys flush excess glucose, supporting steadier blood sugar, lower insulin levels, and gradual weight loss.
From $142.80/mo$210.00/mo
Billed quarterly with a three-month commitment paid up front.
“Bexagliflozin lowers the renal threshold for glucose, routing roughly 280 calories per day of excess glucose into the urine and shifting substrate utilization toward fat oxidation.”
Why Brenzavvy®
Your kidneys reabsorb glucose. Brenzavvy® can reduce that reabsorption.
With Brenzavvy®
Without Brenzavvy®
In a 24-week trial of 207 adults with type 2 diabetes, Brenzavvy lowered HbA1c by 0.4% more than placebo.
Source: FDA-Approved Prescribing Information for Bexagliflozin (Brenzavvy), Clinical Trials 1 & 2, 2025
A review of eight clinical trials found Brenzavvy lowered blood sugar, reduced body weight by 1.8 kg, and dropped systolic blood pressure by 4 mmHg compared to placebo.
Source: Dholariya et al., Expert Opinion on Pharmacotherapy (2023) — Systematic Review & Meta-Analysis of Bexagliflozin Trials
BRENZAVVY® MECHANISM OF ACTION
Kidney support. Glucose control.
Brenzavvy® works on one mechanism in your kidneys with three potential benefits: less glucose reabsorption and steadier blood sugar.
Step 1
SGLT2 blocked
SGLT2 is a kidney protein that recycles roughly 90% of filtered glucose back into your blood. Brenzavvy® can block it, cutting reabsorption by 30–60%.
Step 2
Glucose excreted
Once blocked, glucose leaves through your urine instead of being recycled. This can help lower blood sugar levels without requiring insulin.
Step 3
Metabolic shift
The glucose your body flushes out carries calories with it. Over time, this can support gradual weight loss and may reduce strain on the heart and kidneys.
ABOUT BRENZAVVY®
What to know
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